| 1 | 28th Sep | 11:00am | Challengers Comets | 28 | v | 38 | Churchdown Ladies Blacksox | OxstallS Arena Ct1 | |
| 2 | 5th Oct | 3:30pm | Challengers Comets | 39 | v | 40 | Randwick Embers | OxstallS Arena Ct1 | |
| 3 | 12th Oct | 11:00am | Challengers Comets | 43 | v | 44 | Hartpury University | OxstallS Arena Ct1 | |
| 4 | 19th Oct | 12:30pm | Challengers Comets | 43 | v | 51 | Upton Fire | OxstallS Arena Ct1 | |
| 6 | 16th Nov | 3:30pm | Challengers Comets | 36 | v | 63 | Gloucester Ladies Sapphires | OxstallS Arena Ct1 | |
| 7 | 23rd Nov | 2:00pm | Challengers Comets | 37 | v | 38 | Churchdown Ladies Pinksox | OxstallS Arena Ct1 | |
| 8 | 30th Nov | 12:30pm | Challengers Comets | 43 | v | 30 | Bishops Cleeve Saints | OxstallS Arena Ct1 | |
| 9 | 7th Dec | 2:00pm | Challengers Comets | 23 | v | 45 | Hucclecote Lightning | OxstallS Arena Ct1 | |
| 10 | 14th Dec | 11:00am | Challengers Comets | 32 | v | 29 | Churchdown Ladies Blacksox | OxstallS Arena Ct1 | |
| 11 | 11th Jan | 3:30pm | Challengers Comets | 35 | v | 57 | Randwick Embers | OxstallS Arena Ct1 | |
| 12 | 18th Jan | 11:00am | Challengers Comets | 42 | v | 40 | Hartpury University | OxstallS Arena Ct1 | |
| 13 | 28th Jan | 7:45pm | Challengers Comets | 54 | v | 49 | Upton Fire | Barnwood Park | |
| 14 | 1st Feb | 9:30am | Challengers Comets | 61 | v | 21 | Bishops Cleeve Knights | OxstallS Arena Ct1 | |
| 15 | 8th Feb | 3:30pm | Challengers Comets | 43 | v | 44 | Gloucester Ladies Sapphires | OxstallS Arena Ct1 | |
| 16 | 22nd Feb | 2:00pm | Challengers Comets | 42 | v | 53 | Churchdown Ladies Pinksox | OxstallS Arena Ct1 | |
| 17 | 1st Mar | 12:30pm | Challengers Comets | 45 | v | 40 | Bishops Cleeve Saints | OxstallS Arena Ct1 | |
| 18 | 8th Mar | 2:00pm | Challengers Comets | 43 | v | 49 | Hucclecote Lightning | OxstallS Arena Ct1 | |
| 5 | 15th Mar | Challengers Comets | 36 | v | 29 | Bishops Cleeve Knights | Hartpury |
The following adjustments were applied to Challengers Comets: