| 1 | 21st Sep | 12:30pm | Challengers Galaxy | 33 | v | 25 | Forest Foxes | OxstallS Arena Ct1 | |
| 2 | 28th Sep | 11:00am | Challengers Galaxy | 22 | v | 47 | Seven Up B | Leisure@ Ct1 | |
| 3 | 5th Oct | 12:30pm | Challengers Galaxy | 28 | v | 38 | Cheltenham Ladies Phoenix | Leisure@ Ct1 | |
| 4 | 19th Oct | 11:00am | Challengers Galaxy | 19 | v | 25 | Gloucester City Queens Academy | Leisure@ Ct1 | |
| 5 | 26th Oct | 9:30am | Challengers Galaxy | 45 | v | 30 | Cirencester Aqua | Leisure@ Ct1 | |
| 6 | 16th Nov | 2:00pm | Challengers Galaxy | 16 | v | 40 | Hucclecote Tornadoes | Leisure@ Ct1 | |
| 7 | 23rd Nov | 10:00am | Challengers Galaxy | 27 | v | 27 | Steelers Inferno | High School Leckhampton | |
| 8 | 30th Nov | 10:00am | Challengers Galaxy | 35 | v | 21 | Wildcats Panthers | High School Leckhampton | |
| 9 | 7th Dec | 11:30am | Challengers Galaxy | 34 | v | 37 | Gloucester Ladies Jades | High School Leckhampton | |
| 10 | 14th Dec | 12:30pm | Challengers Galaxy | 37 | v | 29 | Steelers Embers | Leisure@ Ct1 | |
| 11 | 11th Jan | 11:30am | Challengers Galaxy | 23 | v | 39 | Moody Blues | High School Leckhampton | |
| 12 | 18th Jan | 12:30pm | Challengers Galaxy | 27 | v | 32 | Forest Foxes | Leisure@ Ct1 | |
| 13 | 25th Jan | 11:00am | Challengers Galaxy | 33 | v | 51 | Seven Up B | Leisure@ Ct1 | |
| 14 | 1st Feb | 12:30pm | Challengers Galaxy | 34 | v | 38 | Cheltenham Ladies Phoenix | Leisure@ Ct1 | |
| 15 | 8th Feb | 11:00am | Challengers Galaxy | 30 | v | 30 | Gloucester City Queens Academy | Leisure@ Ct1 | |
| 16 | 15th Feb | 9:30am | Challengers Galaxy | 28 | v | 40 | Cirencester Aqua | Leisure@ Ct1 | |
| 17 | 22nd Feb | 2:00pm | Challengers Galaxy | 15 | v | 37 | Hucclecote Tornadoes | Leisure@ Ct1 | |
| 18 | 1st Mar | 10:00am | Challengers Galaxy | 29 | v | 27 | Steelers Inferno | High School Leckhampton | |
| 19 | 8th Mar | 10:00am | Challengers Galaxy | 43 | v | 24 | Wildcats Panthers | High School Leckhampton | |
| 20 | 15th Mar | 11:30am | Challengers Galaxy | 34 | v | 18 | Gloucester Ladies Jades | High School Leckhampton | |
| 21 | 22nd Mar | 12:30pm | Challengers Galaxy | 32 | v | 29 | Steelers Embers | Leisure@ Ct1 | |
| 22 | 29th Mar | 11:30am | Challengers Galaxy | 33 | v | 47 | Moody Blues | Leisure@ Ct2 |