| 1 | 14th Sep | 1:30pm | Home | ENC Equinox | 34 | v | 45 | Bristol Romans Black | Exeter University Sports Park, EX4 4QN | |
| 2 | 21st Sep | 11:30am | Home | ENC Equinox | 54 | v | 48 | Team Bath A | Exeter University Sports Park, EX4 4QN | |
| 3 | 5th Oct | 12:30pm | Away | Bristol Romans Purple | 45 | v | 44 | ENC Equinox | Chelleram Sports Centre, BS8 3QD | |
| 4 | 12th Oct | 12:30pm | Away | Hucclecote Hartpury | 61 | v | 32 | ENC Equinox | Cheltenham College Sports Centre, GL53 7AH | |
| 5 | 26th Oct | 11:30am | Home | ENC Equinox | 49 | v | 45 | Saints Force | Exeter University Sports Park, EX4 4QN | |
| 6 | 2nd Nov | 2:30pm | Away | Mavericks Eagles | - | v | - | ENC Equinox | Chelleram Sports Centre, BS8 3QD | |
| 7 | 16th Nov | 11:30am | Home | ENC Equinox | - | v | - | Poole | Exeter University Sports Park, EX4 4QN | |
| 8 | 23rd Nov | 11:30am | Away | Bournemouth Ferns | - | v | - | ENC Equinox | Bournemouth Collegiate School, BH5 2DY | |
| 9 | 7th Dec | 11:30am | Home | ENC Equinox | - | v | - | Challengers Rockets | Exeter University Sports Park, EX4 4QN | |
| 10 | 14th Dec | 12:30pm | Away | Bristol Romans Black | - | v | - | ENC Equinox | Chelleram Sports Centre, BS8 3QD | |
| 11 | 11th Jan | 12:30pm | Away | Team Bath A | - | v | - | ENC Equinox | Prior Park School, BA2 5AH | |
| 12 | 18th Jan | 11:30am | Home | ENC Equinox | - | v | - | Bristol Romans Purple | Exeter University Sports Park, EX4 4QN | |
| 13 | 8th Feb | 1:30pm | Home | ENC Equinox | - | v | - | Hucclecote Hartpury | Exeter University Sports Park, EX4 4QN | |
| 14 | 15th Feb | 11:00am | Away | Saints Force | - | v | - | ENC Equinox | Truro College (Lynher Building), TR1 3XX | |
| 15 | 1st Mar | 11:30am | Home | ENC Equinox | - | v | - | Mavericks Eagles | Exeter University Sports Park, EX4 4QN | |
| 16 | 8th Mar | 10:30am | Away | Poole | - | v | - | ENC Equinox | Canford Sports Centre, BH21 3AD | |
| 17 | 22nd Mar | 11:30am | Home | ENC Equinox | - | v | - | Bournemouth Ferns | Exeter University Sports Park, EX4 4QN | |
| 18 | 29th Mar | 10:30am | Away | Challengers Rockets | - | v | - | ENC Equinox | TBC |