| 3rd Sep | 8:00pm | Plymouth Sirens | 27 | v | 17 | Beacon Belles | |||
| 10th Sep | 7:00pm | Plymouth Sirens | 25 | v | 33 | PRNC Harlequins | |||
| 17th Sep | 9:00pm | Plymouth Sirens | 25 | v | 40 | SWCH | |||
| 24th Sep | 7:00pm | Plymouth Sirens | 24 | v | 35 | Musketeers | |||
| 8th Oct | 8:00pm | Plymouth Sirens | 33 | v | 39 | Cyan Tigers | |||
| 22nd Oct | 9:00pm | Plymouth Sirens | 23 | v | 38 | Citybus Sparks | |||
| 29th Oct | 7:00pm | Plymouth Sirens | 35 | v | 32 | Kitworld Mako | |||
| 12th Nov | 8:00pm | Plymouth Sirens | 23 | v | 43 | University 5 | |||
| 19th Nov | 9:00pm | Plymouth Sirens | 13 | v | 34 | Plymstock Panthers | |||
| 14th Jan | 8:00pm | Plymouth Sirens | 26 | v | 27 | Cyan Tigers | |||
| 28th Jan | 8:00pm | Plymouth Sirens | 17 | v | 49 | University 5 | |||
| 4th Feb | 7:00pm | Plymouth Sirens | 13 | v | 29 | Citybus Sparks | |||
| 11th Feb | 7:00pm | Plymouth Sirens | 12 | v | 50 | Plymstock Panthers | |||
| 25th Feb | 9:00pm | Plymouth Sirens | 23 | v | 37 | Kitworld Mako | |||
| 17th Mar | 9:00pm | Plymouth Sirens | - | v | - | PRNC Harlequins | |||
| 31st Mar | 8:00pm | Plymouth Sirens | - | v | - | Beacon Belles | |||
| 14th Apr | 7:00pm | Plymouth Sirens | - | v | - | SWCH | |||
| 21st Apr | 8:00pm | Plymouth Sirens | - | v | - | Musketeers |