| 8th Oct | 7:00pm | University 5 | 34 | v | 36 | Citybus Sparks | |||
| 15th Oct | 9:00pm | University 5 | 34 | v | 9 | Beacon Belles | |||
| 22nd Oct | 7:00pm | University 5 | 36 | v | 34 | Cyan Tigers | |||
| 29th Oct | 9:00pm | University 5 | 17 | v | 16 | Plymstock Panthers | |||
| 5th Nov | 8:00pm | University 5 | 37 | v | 27 | SWCH | |||
| 12th Nov | 8:00pm | University 5 | 43 | v | 23 | Plymouth Sirens | |||
| 19th Nov | 8:00pm | University 5 | 23 | v | 31 | Musketeers | |||
| 26th Nov | 7:00pm | University 5 | 36 | v | 24 | PRNC Harlequins | |||
| 3rd Dec | 9:00pm | University 5 | 29 | v | 26 | Kitworld Mako | |||
| 14th Jan | 9:00pm | University 5 | 26 | v | 29 | Citybus Sparks | |||
| 21st Jan | 7:00pm | University 5 | 33 | v | 38 | Kitworld Mako | |||
| 28th Jan | 8:00pm | University 5 | 49 | v | 17 | Plymouth Sirens | |||
| 4th Feb | 9:00pm | University 5 | 44 | v | 19 | Cyan Tigers | |||
| 11th Feb | 8:00pm | University 5 | 28 | v | 32 | Musketeers | |||
| 18th Feb | 7:00pm | University 5 | 1 | v | 0 | Beacon Belles | |||
| 25th Feb | 7:00pm | University 5 | 20 | v | 28 | Plymstock Panthers | |||
| 3rd Mar | 8:00pm | University 5 | 49 | v | 18 | SWCH | |||
| 10th Mar | 9:00pm | University 5 | 52 | v | 20 | PRNC Harlequins |
The following adjustments were applied to University 5: