| 1 | Away | Crossbow | 53 | v | 55 | Devizes | ||||
| 2 | Away | Raychem | 49 | v | 56 | Devizes | ||||
| 3 | Home | Devizes | 40 | v | 39 | Hucclecote Hurricanes | ||||
| 4 | Away | Team Bath C | 41 | v | 61 | Devizes | ||||
| 5 | Home | Devizes | 56 | v | 35 | TJ Saracens | ||||
| 7 | Home | Devizes | 58 | v | 44 | Imperial Royals | ||||
| 8 | Home | Devizes | 47 | v | 38 | Nationwide | ||||
| 12 | Away | Hucclecote Hurricanes | 49 | v | 41 | Devizes | ||||
| 10 | Home | Devizes | 46 | v | 49 | Crossbow |
09/01/22 Devizes v Crossbow postponed due to Covid (Crossbow)
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| 14 | Away | TJ Saracens | 37 | v | 63 | Devizes | ||||
| 15 | Home | Devizes | 55 | v | 39 | Challengers Rockets | ||||
| 16 | Away | Imperial Royals | 43 | v | 62 | Devizes | ||||
| 17 | Away | Nationwide | 45 | v | 58 | Devizes | ||||
| 13 | Home | Devizes | 61 | v | 46 | Team Bath C |
06/02/22 match Devizes v Team Bath C postponed due to Covid (Team Bath)
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| 18 | Away | Bournemouth Ferns | 62 | v | 53 | Devizes | ||||
| 11 | Home | Devizes | 66 | v | 49 | Raychem |
16/01/22 match Devizes v Raychem postponed due to Covid (Raychem)
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| 9 | Home | Devizes | 60 | v | 51 | Bournemouth Ferns |
12/12/2021 match postponed. Date tbc
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| 6 | Away | Challengers Rockets | 49 | v | 48 | Devizes |
07/11/21 match postponed due to Covid (Devizes). Due to be played on 26/03/22 but postponed again.
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