| 1 | 25th Sep | 9:30am | Home | Challengers Galaxy | 47 | v | 31 | Stroud Vipers | Oxstalls Arena (Court 3) | |
| 2 | 2nd Oct | 3:30pm | Home | Challengers Galaxy | 51 | v | 37 | Cheltenham Ladies Phoenix | Oxstalls Arena (Court 3) | |
| 3 | 9th Oct | 9:30am | Home | Challengers Galaxy | 28 | v | 57 | Hucclecote Thunder | Oxstalls Arena (Court 3) | |
| 4 | 16th Oct | 11:30am | Away | Randwick Flash | 42 | v | 27 | Challengers Galaxy | St Peters School | |
| 6 | 13th Nov | 1:00pm | Away | Randwick Sparks | 21 | v | 50 | Challengers Galaxy | St Peters School | |
| 7 | 20th Nov | 9:30am | Away | Steelers Flames | 41 | v | 56 | Challengers Galaxy | Oxstalls Arena (Court 3) | |
| 8 | 27th Nov | Home | Challengers Galaxy | Won | v | Conc | Cirencester Aqua | |||
| 9 | 11th Dec | 11:00am | Home | Challengers Galaxy | 43 | v | 31 | United Hawks | Oxstalls Arena (Court 3) | |
| 11 | 8th Jan | 3:30pm | Home | Challengers Galaxy | 41 | v | 35 | Cheltenham Ladies Phoenix | Oxstalls Arena (Court 3) | |
| 12 | 15th Jan | 11:00am | Home | Challengers Galaxy | 34 | v | 46 | Hucclecote Thunder | Oxstalls Arena (Court 3) | |
| 13 | 22nd Jan | 11:00am | Away | Randwick Flash | 30 | v | 29 | Challengers Galaxy | Oxstalls Arena (Court 3) | |
| 5 | 30th Jan | Home | Challengers Galaxy | 48 | v | 41 | Churchdown Ladies Whitesox | |||
| 14 | 5th Feb | 3:30pm | Home | Challengers Galaxy | 45 | v | 29 | Churchdown Ladies Whitesox | Oxstalls Arena (Court 1) | |
| 15 | 12th Feb | 12:30pm | Away | Randwick Sparks | 36 | v | 42 | Challengers Galaxy | Oxstalls Arena (Court 3) | |
| 16 | 5th Mar | 1:00pm | Away | Steelers Flames | 53 | v | 22 | Challengers Galaxy | St Peters School | |
| 17 | 12th Mar | 11:00am | Home | Challengers Galaxy | 40 | v | 13 | Cirencester Aqua | Oxstalls Arena (Court 3) | |
| 18 | 26th Mar | 11:30am | Home | Challengers Galaxy | 42 | v | 35 | United Hawks | St Peters School | |
| 10 | 9th Apr | 9:30am | Home | Challengers Galaxy | 38 | v | 39 | Stroud Vipers | Oxstalls Arena ( Court 3) |
The following adjustments were applied to Challengers Galaxy: